Poster Presentation 25th Lorne Cancer Conference 2013

Conventional Forceps or Hot Biopsy: Comparative Study of Two Methods in Diagnosis of Endobronchial Lesions (#256)

Mojtaba Lotfalian 1 , Hamidreza Jabbari 2 , Mohammad Fakhri 1 , Arda Kiani 2
  1. Shahid Beheshti Medical University, Tehran, Tehra, Iran
  2. Chronic Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Background: It is suggested that hot electrocoagulation-enabled forceps (hot biopsy) may reduce hemorrhage risk after the biopsy in endobronchial tumors. The main concern in this method is possible reduction of the specimen’s quality.

Objectives: To compare the procedure related hemorrhage with hot biopsy and conventional forceps biopsy and the diagnostic quality of the with either techniques.

Methods: In this prospective study, assessment of the biopsy samples and quantity of hemorrhage were done in a blind fashion. At first, for each patient a definite clinical diagnosis was made based on pathologic examination of all available samples, clinical data, and imaging findings. Then, second pathologist reviewed all samples to evaluate the quality of the samples.

Results: A total of 36 patients with endobronchial lesions were included in this study. The mean hemorrhage grades of all hot biopsy protocols were significantly lower as compared to that of conventional biopsy (p=0.003, p<0.001 and p<0.001 for 10, 20 and 40 voltages respectively). No significant difference was detected between the diagnostic qualities of specimens obtained by hot biopsy methods in comparison with conventional biopsy (p>0.05 for all three voltages).

Conclusions: Hot biopsy can be a valuable alternative to forceps biopsy in evaluating endobronchial lesions.