7:30PM - 10:00PM
Thursday, 14th February
Exhibition Hall
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Targeting glucose metabolism - a strategy for overcoming drug resistance in breast cancer -
Santhi Achuthan
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Coordinate methylation of the alkaline phosphatase gene family in colon cancer. Implications for understanding the manifestation of the CpG island methylator phenotype (CIMP) -
Sheren J Al-Obaidi
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Investigating the function of the novel nuclear protein Manp. -
James Allen
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Evaluation the Biological activity of a computationally de novo deign Peptide in Skin Cancer Cells in vitro -
Nahlah Almansour
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Lmo2 induced precancerous stem cells (pre-CSCs) require Notch and IL-7 signalling pathways for survival. -
Raed F Alserihi
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UNCOUPLING THE p53-DEPENDENT AND INDEPENDENT CELL CYCLE CHECKPOINTS UPON INHIBITION OF POL I TRANSCRIPTION -
Marcia Amalia
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Cytotoxic effects of pineapple bromelain in gastrointestinal carcinoma cell lines -
Afshin Amini
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SR protein splicing factors regulate stem cell properties -
Minna-Liisa Anko
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Impact of overexpression of pro-survival proteins on the development and treatment of MLL-AF9 acute myeloid leukaemia -
Natasha Anstee
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Cancer Drug Discovery: ACRF Drug Discovery Centre for Childhood Cancer -
Greg M Arndt
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New implication for an old drug: minocycline as a potential candidate for the treatment of ovarian cancer-induced malignant ascites -
Parvin Ataie Kachoie
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The expression of Dicer and Drosha in lymph node metastases of triple negative breast cancer. -
Kelly A Avery-Kiejda
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Monepantel suppress ovarian cancer cell proliferation by arresting cell cycle at G1 and down regulating cycline A and E, Cdk 2 and 4 -
Farnaz Bahrami B.
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Cyclin-dependent kinase inhibitor Dinaciclib (SCH 727965) induces apoptosis of MLL-AF9 murine tumour cells -
Adele J Baker
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Potential markers for metformin susceptibility in colorectal cancer -
Alice C Barnett
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Heterogeneity and plasticity in melanoma leads to treatment failure and increased invasiveness that can be blocked by targeting TSP-1 and/or SNAIL -
Andreas Behren
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The Transcription Factor Runx2 is Important for Luminal Differentiation in the Pregnant Mammary Gland -
Sarah Best
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An Exploration of the 11q13 Breast Cancer Susceptibility Locus Using 3C and 4C Chromatin Conformation Capture Technologies -
Joshua Betts
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Developing Polyomic Personalised Therapeutic Strategies for Pancreatic Cancer: Molecular Phenotyping for Treating “One Patient at a Time”. -
Andrew V Biankin
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Noxa and Puma are the main drivers of chemotherapy related apoptosis in MLL-AF9 AML -
Rebecca A Bilardi
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microRNA-223 TARGETS STATHMIN AND REGULATES CELL MIGRATION IN MALIGNANT MESOTHELIOMA -
Kimberly A Birnie
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Delineating the tumor suppressive role of Scribble in prostate cancer metastasis -
Yvonne C Borsetti
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Investigating the effect of assay variation in determining whether melanoma follows a CD271-based cancer stem cell model. -
Samantha E Boyle
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Deregulated gp130/Stat3-Driven inflammation in lung cancer development -
Gavin Brooks
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The Transcriptome of Glioblastoma Stem Cells. -
Daniel V Brown
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Recruitment of human telomerase to telomeres -
Tracy M Bryan
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The contribution of stromal caveolin-1 to breast cancer metastasis. -
Allan D Burrows
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Continuous Treatment With Low Concentrations of the Histone Deacetylase Inhibitor LBH589 Induces Terminal Differentiation of Osteosarcoma Cells -
Jason Cain
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Hedgehog Signaling Maintains a Primitive Osteoblast Phenotype in Osteosarcoma -
Jason Cain
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Designing molecular biomarkers of therapeutic response to CX-5461, a first-in-class RNA Polymerase I inhibitor, for an upcoming Phase I clinical trial -
Don P Cameron
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The p53 isoform, Δ133p53 binds to and inhibits the p53 family members, p63 and p73. -
Hamish G Campbell
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SLIRP, a nuclear receptor corepressor, is a tumor suppressor in CRC that regulates cross-talk between the retinoic acid and notch signaling pathways -
Patrick A Candy
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Genome wide RNAi screen to identify regulators of the oncoprotein LMO4 -
Bianca D Capaldo
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The FAcilitates Chromatin Transcription (FACT) protein complex promotes neuroblastoma tumour initiation -
Daniel R Carter
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Mechanisms underlying prostate cancer cell death induced by combinatorial treatment with an HDAC inhibitor and an antiandrogen -
Sarah Carter
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Increasing intracellular bioavailable copper destroys prostate cancer -
Michael A Cater
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An in vitro model of breast cancer dormancy for use in therapy discovery -
Anannya Chakrabarti
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Defining the involvement of the E6AP-PML axis in human prostate cancer. -
Ai-Leen Chan
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LRH-1 regulates hnRNPA1 and A2/B1 expression to modulate proliferation in breast cancer cells -
Ashwini Chand
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Tumour immune infiltrate links tumour metastatic behavior and systemic Neutrophil-Lymphocyte Ratio (NLR) in colorectal cancer patients -
Kellie A Charles
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DNA methylation patterns in pediatric Acute Lymphoblastic Leukemia -
Zac Chatterton
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THE UBIQUITIN LIGASE SIAH IS A NOVEL REGULATOR OF EPITHELIAL-MESENCHYMAL TRANSITION IN BREAST CANCER -
Anna Chen
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HIGH TRIM16 EXPRESSION PREDICTS FAVOURABLE OUTCOME IN PATIENTS WITH METASTATIC MELANOMA -
Belamy Cheung
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INCREASING THE EFFECTIVENESS OF RETINOID ANTICANCER THERAPY FOR NEUROBLASTOMA -
Belamy Cheung
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Diagnostic Serum Biomarkers for Canine Hemangiosarcoma: a Potential Model of Human Angiosarcoma -
Eunju Choi
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Apoptotic sensitivity of tumour cells to HDACi is determined by sustained induction of the immediate-early genes Jun and Atf3. -
Anderly C Chueh
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Characterisation of a novel regulator of Hedgehog signalling, which regulates medulloblastoma tumour growth. -
Sarah E Conduit
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Differentiation and function of Foxp3+effector regulatory T cells. -
Erika Cretney
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Deletion of Myb in keratin 14 expressing cells delays mammary cancer onset -
Ryan Cross
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Whole exome sequence analysis of an in vitro model of drug-resistant T-cell acute lymphoblastic leukaemia -
Mark N Cruickshank
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Parity (childbearing) reduces the numbers of the MaSC-enriched CD24+CD49fhi cells. -
Genevieve Dall
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Oncogenic properties of cAMP Response Element Binding (CREB) protein in brain tumour cells -
Paul Daniel
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Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer -
Sally J Davis
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A novel DNA damage-induced apoptotic pathway cooperates with p53 to enforce tumour suppression -
Alex RD Delbridge
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Determining the Role of Tropomyosins in Actin-Mediated Apoptosis -
Melissa Desouza
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Cooperative killing of MYC-driven B-lymphoma cells by inhibitors of the PI3K/AKT/mTOR pathway and RNA Polymerase I transcription -
Jennifer R Devlin
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Characterisation of pro-invasive transcriptional programs regulated by the Fra-1 transcription factor -
Jeannine Diesch
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Reduced expression of HDAC3 contributes to the resistance against HDAC inhibitor, vorinostat (SAHA) in mature lymphoid malignancies -
Jianmin (Diane) Ding
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Mast Cells and Macrophages are Therapeutic Targets in Inflammation-Associated Gastric Cancer -
Moritz Eissmann
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HoxA9-mediated immortalisation of myeloid progenitors requires Bcl-2 -
Gabriela Brumatti
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Osteogenic differentiation of mesenchymal stem cells by PEDF in alginate microbeads -
Mina Elahy
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A novel murine model of lung cancer that facilitates acceleration of K-RasG12D driven tumourigensis -
Imogen Elsum
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TRAF2 regulates TNF related inflammation and cell death in keratinocytes. -
Nima Etemadi
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Development of Arginine Methyltransferase PRMT5 Inhibitors as Novel Agents for the Treatment of Cancers -
Hendrik Falk
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A Genome-wide screen for novel genes involved in sensitisation to Histone Deacetylase inhibitors -
Katrina J Falkenberg
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MDM4 IS A NOVEL THERAPEUTIC TARGET IN HUMAN MELANOMA -
Clare Fedele
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Differential effects of MUC1 expression in colon cancer cells. -
Harvey R Fernandez
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Inhibition of histone acetyltransferases contributes to the anti-cancer activity of the phenothiazines -
Harvey R Fernandez
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Glucocorticoids inhibit breast tumour cell migration but increase metastasis to the lung in a mouse model of breast cancer -
Ebony R Fietz
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Understanding stathmin’s role in neuroblastoma metastasis -
Christopher Fife
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Differential microRNA expression following transformation of embryonic liver progenitor cells as a model for the development of hepatocellular carcinoma -
Megan Finch
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Investigating the roles of Epstein-Barr virus in the pathogenesis of Burkitt lymphoma -
Leah Fitzsimmons
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Screening for neuroblastoma drugs selectively active in the bone marrow environment -
Jamie I Fletcher
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The pro-tumourigenic role of microglia in glioblastoma multiforme pathogenesis: influence of CypA and CD147 signalling. -
Gurkiran Kaur Flora
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Molecular profiling of Pheochromocytoma -
Aidan Flynn
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Imaging Beyond the Diffraction Limit -
Peter Franklin
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Determinants of acquired chemo-resistance in ovarian cancer -
Sarah Ftouni
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ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer -
David Gallego Ortega
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Expression of each gene of the polyamine pathway is prognostic of outcome and is directly regulated by the MYCN oncogene in neuroblastoma -
Laura Gamble
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E6AP as a novel regulator of the ASPP family members -
Cristina Gamell
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Sensitivity to dichloroacetate is determined by PDK expression -
Bevan P Gang
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Dysregulation of the repressive H3K27 trimethylation mark in head and neck squamous cell carcinoma contributes to dysregulated squamous differentiation -
Orla M Gannon
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A PR55α-containing PP2A complex positively regulates Fra-1/c-Jun function in tumour cells -
Omer Gilan
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Axl drives the development of acquired resistance to tyrosine kinase inhibitor therapy in head and neck cancer -
Keith M Giles
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Role of pro‐survival BCL-2 family members in haematopoiesis and acute myeloid leukemia. -
Stefan P Glaser
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Co-Culturing Prostate Cancer Cells with Bone Stromal Cells:A Reciprocal Interaction -
Tristan T Glover
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The asymmetric cell division regulator GPSM2 controls mammary progenitor activity and breast cancer progression. -
Nathan J Godde
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Phylogenetic analysis of clonal evolution of acquired drug resistance in liposarcoma -
David Goode
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Mitochondrial-STAT3 supports K-Ras induced myeloproliferative disease in vivo. -
Daniel J Gough
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Mitochondrial-STAT3 dependent regulation of glutathione synthesis is a tumour specific vulnerability. -
Daniel Gough
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Stephanie Grabow
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Mcl-1 sustains survival of Myc over-expressing pre-leukaemic B lymphoid cells in Eμ-myc transgenic mice -
Stephanie Grabow
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Glioblastoma-specific Domain IV mutations in the EGFR are able to covalently dimerise in response to ligand and the small molecule inhibitors gefitinib and erlotinib. -
Sameer A Greenall
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A double strike against leukaemia: Dual targeting of PI3K and Cdk9 rapidly and selectively induces apoptosis in human AML cells. -
Mark Guthridge
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Targeted deletion of ILK in tumour-initiating cells improves survival of mice with highly aggressive Hedgehog-driven medulloblastoma. -
Gregory E Hannigan
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Folic acid promotes tumour growth and STAT3 activation -
Mariann Fagernaes Hansen*
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Mitochondrial Mutations and Metabolic Profiling of Pancreatic Cancer -
Rae-Anne Hardie
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Combined targeted expression of the Pik3caH1047R and Apc mutations in the gastrointestinal tract causes invasive adenocarcinomas -
Lauren M Hare
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APPLICATION OF IMAGING TECHNOLOGIES IN THE PRECLINICAL DEVELOPMENT OF NOVEL ONCOLOGY AGENTS -
Athena Hatzimihalis
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Tumour manifestation is dictated by PML in a gender-specific manner in a mutant p53 cancer model -
Sue Haupt
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Yeast techniques for modelling drugs targeting Bcl-2 and caspase family members -
Christine J Hawkins
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E2F7 regulates sensitivity to the cytotoxic actions of anthracyclines in squamous cell carcinoma -
Mehlika Hazar Rethinam
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Association of ABCA1 cholesterol transporter with poor outcome and aggressive phenotype in serous ovarian cancer. -
Michelle Henderson
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Mutation of Foxo binding elements in the bim promoter does not abrogate Bim dependent killing -
Marco J Herold
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Differential glycosylation of circulating proteins as diagnostic biomarkers for Barrett’s oesophagus and oesophageal adenocarcinoma -
Michelle M Hill
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Regulation of colorectal tumor-initiating cells by the tight junction protein claudin-2. -
Fred Hollande
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Cancer metastasis via the blood circulation promoted by novel proteolytic mechanisms -
John D Hooper
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Connective tissue growth factor is increased in pre-B acute lymphoblastic leukaemia and mediates leukaemia - stromal cell interactions -
Meegan Howlett
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Improving patient immune responses to monoclonal antibody therapies in epithelial cancer through changes in cellular trafficking and signaling pathways. -
Lingbo Hu
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Improving patient immune responses to monoclonal antibody therapies in epithelial cancer through changes in cellular trafficking -
Lingbo Hu
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TSP-1 expression in melanoma correlates with EMT and increased invasiveness -
Christopher Hudson
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HIGH-RESOLUTION MOLECULAR PROFILING OF PRE-INVASIVE EPITHELIAL OVARIAN TUMOURS -
Sally M Hunter
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Defining the Role of E3 Ubiquitin Ligase UBR5 in Cancer Through Substrate Identification -
Mary Iconomou
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PTRF/cavin-1 modulates exosome content and function -
Kerry L Inder
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Harnessing the tumour adaptive response to hypoxia to identify novel combinations of the vascular disrupting agent BNC105 with targeted therapeutics. -
Daniel J Inglis
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Interleukin-3 signalling responses in myeloid cells -
Anissa Jabbour
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The homeobox transcription factor Hhex regulates haematopoietic stem cell cycling and emergency haematopoiesis. -
Jacob T Jackson
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A crucial role for the homeobox transcription factor Hhex in lymphogenesis. -
Jacob T Jackson
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Investigating the effects of lymphoma mutations enhancing NFκB signalling -
Yogesh Jeelall
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Normal breast epithelial subpopulations exhibit different responses to radiation induced DNA damage -
Rebecca L Johnston
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Potential roles for thrombopoietin and platelets in lymphoma -
Emma C Josefsson
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A critical role for ID4 in mammary stem cells and triple negative breast cancer -
Simon Junankar
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Association of Myc oncogene family expression with patient outcome in ovarian and colorectal carcinomas -
MoonSun Jung
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The partially-assembled GM-CSF receptor hexameric complex mediates cell survival -
Winnie LT Kan
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Characterization of molecular features of MYC dependence and identification of a synthetic lethal interaction between MYC and CDK1 in human breast cancer cells -
Jian Kang
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B-CELL ACTIVATING FACTOR (BAFF) PROMOTES LYMPHOMAS BY UPREGULATING TELOMERASE ACTIVITY IN B LYMPHOCYTES -
Indzi Katik
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Inhibitors of Mitochondrial Apoptotic Pathway in Parapox virus -
Livleen Kaur
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Functional interactions between p53 and anti-apoptotic Mcl-1 in sustaining the survival and growth of Myc-driven lymphoma. -
Gemma L Kelly
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Breast Cancer in Pakistan, A review of current Situation. -
Ammara Khalid
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Runx oncoproteins regulate cell fate decisions leading to senescence or survival. -
Anna Kilbey
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Combined targeting of JAK2 and Bcl-2/Bcl-xL as a novel treatment strategy in JAK2-driven B-cell precursor Acute Lymphoblastic Leukemia (BCP-ALL) -
Sang Kyu Kim
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Effects of Novel HDAC Inhibitors on the Proliferation, Colony Formation and Radiosensitivity of Brain Metastatic Breast Cancer Cells -
Soo Kim
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Implications of Fc-engineering to a humanised anti-Ley antibody on Fc gamma receptor binding -
Dylan T King
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Identification of Caspase-2 Specificity and Substrates -
Tanja Kitevska
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The effect of netrin-1 on colorectal cancer cells and its malignant properties -
Suhyoun Ko
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DISCOVERY OF NOVEL TELOMERASE INHIBITORS AND BINDING MODE PREDICTION -
Manju Latha Krishna Moorthy
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Thrombospondin 4 is upregulated in breast cancer-associated stroma -
Jamie R Kutasovic
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A High Throughput Screening Platform for the Identification of Small Molecule Inhibitors of the Ubiquitin E3 Ligase E6AP -
Kurt Lackovic
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IAPs limit RIPK1-induced TNF biosynthesis -
Najoua Lalaoui
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Chronic stress enhances progression of acute lymphoblastic leukemia through beta-adrenergic signaling -
Donald M Lamkin
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Mixl1 expression in human leukemias and lymphomas -
Katherine K Lange
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Understanding the roles of exosomes during epithelial-mesenchymal transition -
Anh VP. Le
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Bcor loss-of-function mutations cooperate with Myc to drive lymphomagenesis in Eμ-Myc lymphoma. -
Marcus Lefebure
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Discovery, Structure-Guided Design and Biological Validation of the First Potent and Selective Inhibitor of the Pro-Survival BCL-2 Family Member BCL-XL -
Guillaume Lessene
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Receptor Tyrosine Kinases differ in their ability to confer resistance to Vemurafenib (PLX4032) treatment in BRAFV600E melanoma. -
Frederic Li
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Targeting of Hedgehog pathway via pharmacologic inhibition of Gli induces apoptosis and autophagy in malignant mesothelioma cells -
Chuan Bian Lim
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Sorting nexin 5 is a regulator of macropinocytosis in macrophages which also affects cell proliferation -
Jet Phey Lim
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Structural biology of Scribble protein -
Krystle Lim
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Identification of the determinants in CSK-Homologous Kinase (CHK) essential for its tumour suppressor function -
Ya Chee Lim
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Medical utilization and cost of liver cancer under National Health Insurance in Taiwan: a population-based cross-sectional study -
Yi-Hsien Lin
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Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor -
Lisa M Lindqvist
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Re-engaging the Pax5-dependent transcriptional program in B progenitor acute lymphoblastic leukemia causes tumour differentiation and clearance -
Grace J. Liu
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Small molecule inhibitors of ICMT as potential cancer therapeutics -
Aaron M Lock
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Risk Factors Affecting the Survival Rate in Patients with SymptomaticPericardial Effusion Underwent Surgical Intervention -
Mojtaba Lotfalian
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Conventional Forceps or Hot Biopsy: Comparative Study of Two Methods in Diagnosis of Endobronchial Lesions -
Mojtaba Lotfalian
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Effects of Protein Arginine Methyltransferase 5 Knockdown or Inhibition on Tumour Cell Growth -
Kym Lowes
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The characterisation of Adenomatous polyposis coli (APC) at the centrosome -
Christina Lui
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Mechanistic basis for loss of cellular differentiation in colon cancer -
Ian Y Luk
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DIFFERENTIAL EFFECTS OF STORE OPERATED CALCIUM ENTRY PROTEINS ON THE CALCIUM-MEDIATED TRANSCRIPTION FACTORS NFκB AND NFAT IN MDA-MB-231 BREAST CANCER CELLS -
Nicole A Luk
7:30PM - 10:00PM
Friday, 15th February
Exhibition Hall
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Orphan Nuclear Receptor NUR77: A Potential Biomarker of Response to Epigenetic Treatment of Myelodysplasia -
HongBin Liu
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Integrated genomics for prostate cancer -
Geoff Macintyre
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Significant numbers of metabolically active irradiated tumour cells enter the circulation during a course of fractionated radiation therapy for non-small cell lung cancer: A novel finding with potential clinical significance -
Michael P MacManus
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Proteomic analysis of 9 glioblastoma multiforme cell lines -
Duthika Mallawaaratchy
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A systematic approach to identify novel cooperative tumour suppressor genes in Ras-driven tumourigenesis -
Jan Manent
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The E3-ligase E6AP controls breast cancer invasion and motiliy by regulation of Rho-GTPases proteins -
Mariam Mansour
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A synthetic-lethal screen for innate platinum resistance genes in lung adenocarcinoma -
Kieren Marini
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Investigating the Inhibitory and Radiosensitising Properties of Dietary Polyphenols Resveratrol and [10]-Gingerol Against Metastatic Breast Tumour Cells -
Ana Carolina Martin
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The relationship between Scribble structure, localisation and function -
Claire A Martin
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Human epithelial ovarian cancer cell lines differentially express Sprouty proteins 1, 2 and 4 -
Samar Masoumi Moghaddam
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Regulation of BH3-only proteins downstream of IL-3 and GM-CSF signalling -
Dimitra Masouras
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Target gene identification of microRNAs associated with lymph node metastases in triple negative breast cancer -
Andrea Mathe
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Reduced proliferation of murine B-cell lymphoma and acute myeloid leukaemia through RNAi-mediated loss of HDAC 3 occurs in a p53-dependent manner -
Geoffrey Matthews
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TEMs (Tie2 Expressing Monocytes): Novel targets and effectors of anti-cancer therapies -
Roberta Mazzieri
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Loss of the Tumor Suppressor Gene HIC1 Promotes Oncogenic Transformation in Mouse Embryonic Fibroblasts -
Lisa McKenzie
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DNA Adduct-Forming Derivatives of the Anticancer Agents Mitoxantrone and Pixantrone -
Jelena Medan
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Role of 2-morpholine substituted-1,3-benzoaxine family of compounds as chemo-sensitising agents, independent of DNA-PK -
Terri Meehan-Andrews
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Phosphotyrosine profiling to define new therapeutic targets in infant MLL -
Agnes Mendomo
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Cis-regulation of non-codings RNAs within the HOXC locus in breast cancer -
Michael Milevskiy
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Role of APC in Mitochondrial Transport -
Kate Mills
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Therapeutic and Research Potential of Stem cells -
Stephen Minger
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Leptin increases the metastatic potential of breast cancer cells. -
Ameet K. Mishra
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Plasma vitronectin predicts response to fluoropyrimidine-oxaliplatin chemotherapy in metastatic colorectal cancer -
Mark P Molloy
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Cavin-1 alters oncogenic effects of caveolin-1 microdomains in prostate cancer -
Hyeongsun Moon
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mRNA expression analysis of p53 isoforms in breast cancer -
Brianna Morten
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Different protocols for Cryobiopsy versus Forceps Biopsy in Diagnosis of Patients with Endobronchial Tumors -
amirhossein mozafarykhamseh
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Evaluation of anti-inflammatory kinase inhibitors for glioblastoma therapy -
Lenka Munoz
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Identification and filtering of noisy probes for the Infinium HumanMethylation450 array -
Haroon Naeem
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A Myc transcriptional program that is independent of EMT drives a poor prognosis tumour- propagating phenotype in HER2+ breast cancer -
Radhika Nair
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Loss of ATRX or DAXX facilitates cellular immortalisation via the Alternative Lengthening of Telomeres pathway -
Christine E Napier
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Functional characterization of microRNA isoforms with differential 3’ends -
Corine T Neilsen
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The mutant p53 secretome drives invasion -
Paul M Neilsen
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Elucidating the mechanisms of gene inactivation in a murine p53 shRNA-based Osteosarcoma model -
Alvin JM Ng
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New roles for Interleukin-22 in the promotion of inflammation-associated gastric cancer. -
Paul Nguyen
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L1 Retrotransposition and Somatic Genomic Instability in High-Grade Serous Ovarian Cancer -
Thu H M Nguyen
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Exploiting the receptor uPARAP/Endo180 for targeted delivery of anti-cancer drugs to sarcomas and glioblastomas -
Christoffer Nielsen
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Sex steroid receptor signalling and immune function -
Rebecca Nightingale
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High expression of the telomerase-RNA binding protein dyskerin contributes to the proliferation and survival of neuroblastoma cells and is predictive of poor patient outcome -
Rosemary O'Brien
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Hck Drives Tumour Associated Macrophage Transcriptional Profiles in Myeloid Cells Promoting Pulmonary Inflammation and Cancer. -
Robert JJ O'Donoghue
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Kinetic modelling and the intrinsic apoptosis pathway -
Martin O'Hely
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Jersey regulates mammary development and plays a key role in human breast carcinogenesis. -
Samantha R Oakes
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Epigenomes of mouse mammary epithelial subsets -
Bhupinder Pal
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Understanding Oncogenic PI3K in Colorectal Cancer -
Michelle Palmieri
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Phosphoproteomics of cellular response to Vemurafenib reveals reprogramming by oncogenic B-RAF protein in Thyroid Cancer -
Rob Parker
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A Bifunctional Fluorescent Assay for the Assessment of Cytotoxicity and Proliferation -
Rachael Parry
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Molecular Changes Associated with Transformation of Liver Progenitor Cells -
Adam Passman
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A telomere protective function of hTERT that is independent of catalytic activity. -
Omesha Perera
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Therapeutic Approach to Target Mesothelioma Cancer Cells Using the Wnt Antagonist sFRP4: Metabolic State Of Cancer Cells -
Vanathi Perumal
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A bioinformatic pipeline for the analysis of miRNAs in the PMC42 and MDA-MB-468 model systems of human breast cancer. -
Gayle K Philip
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Identification and functional characterisation of miRNAs in breast development and malignancy -
Yuwei Phua
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Variant repeats are interspersed throughout the telomeres of ALT cells, resulting in altered telomeric architecture -
Hilda A Pickett
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A Single Transcriptional Program Underpins Patient Survival in Pancreatic Cancer -
Mark Pinese
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An in vitro assay to screen novel potential driver genes of pancreatic carcinogenesis -
Andreia V. Pinho
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Understanding Cancer Cell Populations in Breast Cancer – A Functional Genomics Approach -
Cletus A Pinto
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Targeting a Novel MicroRNA Angiogenesis Pathway as a Next Generation Cancer Therapy -
Prue N Plummer
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Haematopoietic Cell Kinase Promotes the Development and Progression of Colorectal Cancer in Mice. -
Ashleigh Poh
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SOX11 as a potential target of FUS-DDIT3 in Myxoid Liposarcoma -
Sophie Popkiss
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A DISINTEGRIN AND METALLOPROTEINASE ADAM-9 REGULATES THE METASTATIC PROPERTIES OF BREAST TUMOUR CELLS -
Normand Pouliot
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Investigating modes of action for Pixantrone cytotoxicity and lack of cardiotoxicity -
Paul P Pumuye
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Cytokines as key targets in cancer related inflammation -
Tracy Putoczki
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A Novel Inhibitor of Ribosomal RNA Gene Transcription Identifies both p53-Dependent and p53-Independent Checkpoint Responses to Perturbation of Pol I Transcription -
Jaclyn Quin
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Genomic analysis of human brain metastases: an integrative approach -
Michael C J Quinn†
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RADIOSENSITIZING EFFECT OF BENZ 1, 3-OXAZINES AS NOVEL DNA-PK INHIBITORS IN THE TREATMENT OF CANCER -
Suraj Radhamani
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Deconstructing the invasive machinery of cancer cells. -
Troy J Ralph
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An siRNA screen to identify novel regulators of the cell cycle G2/M transition. -
Max V. Ranall
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The anti-angiogenic properties of sulfated β-cyclodextrins in anti-cancer formulations incorporating 5-fluorouracil -
Marie Ranson
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Stimulating the innate type-1 interferon pathway reduces breast cancer metastasis to bone -
Jai Rautela
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Shifting doxorubicin activity from topoisomerase2 poison to adduct formation reduces cardiotoxicity while maintaining anticancer efficacy -
David M Rayner
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Can cell death drive TNF dependent skin inflammation? -
James Rickard
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PRIOR TO THE ONSET OF ADVANCED DISEASE, CANCER REPOPULATING CELLS IN LOCALISED PROSTATE TUMOURS ARE CASTRATE-RESISTANT AND STEM-LIKE. -
Gail Risbridger
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CAPTIV: The Cancer of Prostate Translational Research in Victoria Collaboration -
Gail P Risbridger
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Identification of new BIM regulators using over-expression and knockdown libraries -
Leona Rohrbeck
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Sirtuin 1 is a novel regulator of pancreatic carcinogenesis -
Ilse Rooman
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Combination therapy with raloxifene and a novel curcumin analog for the treatment of hormone refractory prostate cancer: in vitro mechanisms for synergistic cytotoxicity -
Rhonda J Rosengren
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Next-Generation Sequence Analysis of Cancer Xenografts -
Fernando Rossello
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Genomic profiling of primary mucinous ovarian carcinomas -
Georgie L Ryland
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Differentiation Therapy for t(8;21) Acute Myeloid Leukemia -
Jessica Salmon
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A novel therapeutic target in high-grade serous ovarian cancer: Connective Tissue Growth Factor (CTGF) -
Goli Samimi
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Bioenergetic modulation sensitises acute lymphoblastic leukaemia to glucocorticoids -
Amy L Samuels
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Identification of microRNAs that function downstream of Brca1 -
Gurveen Sandhu
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Chemokine signalling in breast cancer angiogenesis -
Michael J Sax
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Sex steroid receptor signalling in Flu specific T cells. -
Manvendra Saxena
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Formation of an immunosuppressive pre-metastatic niche in breast cancer triggered by hypoxic tumour-derived factors -
Jaclyn Sceneay
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Investigating DNA methylation in paediatric central nervous system tumours -
Alexandra Sexton-Oates
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Histone deacetylase 2 promotes N-Myc oncogenesis by repressing the transcription of p53 induced nuclear protein 1 -
Jeyran Shahabzi
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Defining Ubiquitin Ligase Function in Breast Cancer -
Robert Shearer
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Mutagenic potential of direct apoptosis inducers -
Tanmay Shekhar
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Targeting MUC13 to sensitise colorectal cancer cells to apoptosis -
Yong H Sheng
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Evaluation of the CDK4 Inhibitor PD-0332991 in Melanoma and Identification of Genomic Predictors of Sensitivity -
Karen E Sheppard
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Hhex regulates therapeutic resistance of Lmo2-induced pre-Cancerous Stem Cells. -
Benjamin J Shields
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RNA aptamers targeting CD133 as a novel targeted therapeutic for the treatment of cancer -
Sarah L Shigdar
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Regulation of the matricellular proteins CCN1/Cyr61 and CCN2/CTGF by vitronectin induces cancer cell survival -
Ali Shokoohmand
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Screen small, diverse compound subsets from the Queensland Compound Library “Open” collection -
Moana M Simpson
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A novel role for pericytes as ‘cancer associated fibroblasts’ in ovarian cancer progression and metastasis -
Devbarna Sinha
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A ROLE FOR THE FREE BETA SUBUNIT OF HUMAN CHORIONIC GONADOTROPIN IN SENSITIVITY OF EPITHELIAL OVARIAN CANCER CELLS TO PLATINUM-BASED CHEMOTHERAPEUTICS -
Snega S Sinnappan
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DNA Damage Response in Peripheral Blood Lymphocytes and Out-of-Field Hair Follicles During Radiotherapy of Patients with Non-Small Cell Lung Cancer: A Prospective Clinical Trial -
Shankar Siva
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GENOME-WIDE GAIN-OF-FUNCTION SCREEN FOR GENES THAT INDUCE EPITHELIAL TO MESENCHYMAL TRANSITION IN BREAST CANCER -
Dubravka Skalamera
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Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter- Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer -
Dubravka Škalamera
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Neural regulation of metastasis: New avenues for therapeutic intervention -
Erica K Sloan
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Inactivation of USP44, a regulator of global H2BK120ub levels, is an early event in the formation of colorectal cancer -
Mathew A. Sloane
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Tumour Suppression via Re-equilibration of Cell Polarity Networks. -
Lorey Smith
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Discovery of microRNAs associated with Breast Cancer Epithelial Mesenchymal Plasticity using Bioinformatics and Next Generation Sequencing -
Eliza Soo
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Flavopiridol – a novel therapeutic option for NUT midline carcinoma -
Anja Stirnweiss
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BCL-2 expression is silenced by DNA hypermethylation in human breast cancer, providing a potential biomarker of sensitivity to mitotic inhibition. -
Andrew Stone
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The loss of Cdkn2a locus is a critical event in the transformation of liver progenitor cells -
Robyn Strauss
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Deletion of Myc limits the growth of Stat3-driven gastric tumours -
Emma C Stuart
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Functional analysis of TERT locus polymorphisms which are associated with risk of breast and ovarian cancer -
Michael D Stutz
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Histone deacetylase 5 forms a transcriptional repressor complex with N-Myc and blocks tumour cell differentiation -
Yuting Sun
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CHARACTERIZATION OF NOVEL DNA-PK INHIBITOR FROM ISOFORM SPECIFIC PI3K AS AN ANTI-CANCER DRUG -
Rejitha Suraj
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High-throughput identification and characterization of novel enhancer molecule for hydroxamate-based histone deacetylase inhibitors -
Aldwin Suryo Rahmanto
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Detection of autophagy - AlphaLISA assays -
Margareta Sutija
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Metastatic tumours promote monocyte mobilisation -
Agnieszka Swierczak
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Role of the unfolded protein response in melanoma progression and metastasis -
Erin K Sykes
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Loss of Tumor Suppressor Hic1 Accelerates the Progression of Lung Adenocarcinoma Induced by Oncogenic KRas -
Anette Szczepny
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Molecular analysis of circulating (CTC) and disseminated tumour cells (DTC) in human breast cancer xenograft models. -
Anthony Tachtsidis
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The atypical kinase SgK223 is a novel mediator of cell invasion in pancreatic cancer -
Carole M Tactacan
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Frequent alterations in mTOR signaling in human ovarian serous carcinomas -
Pradeep Tanwar
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Assessing the regulatory function of small RNAs -
Daniel W Thomson
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Multiple mechanisms of resistance to targeted inhibitors in c-Kit mutant melanoma -
Jason Todd
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Evaluation of the efficacy of bromodomain inhibitors for the treatment of colorectal cancer -
Lars Tögel
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Differential Effects of Oxytocin on Androgen Independent Prostate Cancer Cells -
Nicole C Tom
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A FUNCTIONAL IN VIVO shRNA SCREEN FOR BREAST CANCER METASTASIS SUPRESSOR GENES -
Rebeka Tomasin
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Identification and validation of two novel metastatic markers in Osteosarcoma. -
Eleni Topkas
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Designing targeted therapies for High-Grade Serous Ovarian Cancer (HG-SOC) utilising a novel xenograft cohort stratified according to molecular defects -
Monique D Topp
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Absence of senescence traits in human melanocytic nevi -
Sieu L Tran
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Histone deacetylase and proteasome inhibitors induce overlapping transcriptional responses and synergistically induce apoptosis in tumour cells. -
Janson JT Tse
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The antimicrobial peptide LL-37 inhibits migration of prostate cancer cells -
Yan Tu
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Complete loss of the p53 effectors p21, Puma and Noxa does not predispose mice to spontaneous tumor development -
Liz J Valente
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Understanding the role of tumour suppressor TRIM35 in TGF-ß signaling -
Joanne H. van Vuuren
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A new Bcl-2-specific BH3-mimetic has in vivo efficacy without provoking thrombocytopenia -
Cassandra Vandenberg
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Investigating the role of exosomes in promoting melanoma metastasis. -
Laura J Vella
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Combined targeting of JAK2 and Bcl-2/Bcl-xL as a novel, potentially curative treatment for haematological malignancies expressing mutant JAK2 -
Michaela Waibel
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High-grade mucinous ovarian cancer: from where does it originate and how should it be treated? -
Matthew Wakefield
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MYD88 mutation in B-cells - effects on NFkB activity, B-cell survival and proliferation -
James Q Wang
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STAT3 inhibitor S3I-201 suppresses human osteosarcoma cell growth -
Xiaochun Wang
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Anti-cancer efficacy of histone deacetylase inhibitors mediated by immune system -
Alison C West
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Identifying predictors of sensitivity to PF-00477736 in melanoma -
Britanto Wicaksono
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Dynamic expression of EMT-related mRNA alternative splicing variants in human mammary carcinoma -
Edwin Widodo
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Not so minor after all. Emerging roles for “minor class” splicing in cancer. -
Benjamin B Williams
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In Vivo biomarker expression patterns are preserved in 3D cultures of Prostate Cancer -
Louisa CE Windus
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Defining the gene regulatory network controlled by the tumour suppressor Ikaros in thymocytes and T cell leukemia using dynamic in vivo RNAi -
Matthew Witkowski
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Understanding the mechanism of erythroid enucleation: a chemical genetics approach -
Christina B Woelwer
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E6-Associated Protein (E6AP) regulates the INK4/ARF locus and oncogene-induced senescence -
Kamil Wolyniec
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Achieving increased chemotherapeutic efficacy in breast cancer by loss of Siah2 -
Christina S.F. Wong
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Increased Interferon Response Gene Expression During Megakaryocyte Ontogeny: Implications for the Spontaneous Resolution of Down Syndrome Transient Myeloproliferative Disorder -
Andrew J. Woo
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Novel small molecules that target the dimer interface of 14-3-3 proteins as a basis for possible anti-cancer therapeutics. -
Joanna Woodcock
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Processing and presentation of NY-ESO-1 epitopes by melanoma cells. -
Katherine Woods
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Isolation and characterization of prostate cancer initiating cells based on aldehyde dehydrogenase activity -
Jinhan (Angela) Xie
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mTOR Inhibition in Biliary Tract Cancer -
Yvonne Yeung
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Fibroblast Growth Factor Receptor 1 Gene Amplification in Oral Tongue Squamous Cell Carcinoma - Frequency and Associations with Clinical Features and Patient Outcome -
Richard J Young
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Transcription Factor ATF3 Suppresses Bladder Cancer Metastases by Regulating Gelsolin-Mediated Actin Cytoskeleton Remodeling -
Liang Yu
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Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling -
Luxi Zhang
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Human Breast Cancer Cell Lines and micro-RNAs in the Quail Embryo – A model for short term in vivo responses. -
Tania Zheng
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Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue (FFPET) using MBDCap-Seq identifies novel epigenetic diagnostic biomarker loci in breast cancer -
Elena Zotenko*
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The biological function of parallel telomeric G-quadruplexes and their interaction with the cancer associated enzyme telomerase -
Katherine G Zyner
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Triazolophanes as a novel class of G-quadruplex binding agents -
Lucy Ping
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The inflammation-resolving trihydroxy-docosahexaenoic acid derivative, resolvin D2 supports MCF-7 cell proliferation via activation of estrogen receptor -
Nuha Alzaubai
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The prognostic significance of ALDEHYDE DEHYDROGENASE 1 (ALDH1) and CD133 expression in early-stage non-small cell lung cancer. -
Alamgeer Muhammad